Fluid restricted diet by claudio
Methods Study Design and Treatment Protocol Patients 18 years of age or older who had been admitted to the closed, multidisciplinary ICUs of 16 academic tertiary hospitals in Australia and New Zealand between November 2001 and June 2003 were assessed for eligibility for the study. Figure 2 Relative Risk of Death from Any Cause among All the Patients and among the Patients in the Six Predefined Subgroups. Conclusions In patients in the ICU, use of either 4 percent albumin or normal saline for fluid resuscitation results in similar outcomes at 28 days. Abstract Background It remains uncertain whether the choice of resuscitation fluid for patients in intensive care units (ICUs) affects survival. Participants received quarterly individual and group educational sessions and, depending on group assignment, free provision of extra-virgin olive oil, mixed nuts, or small nonfood gifts. Methods We randomly assigned patients who had been admitted to the ICU to receive either 4 percent albumin or normal saline for intravascular-fluid resuscitation during the next 28 days. 8 years. The two Mediterranean-diet groups had good adherence to the intervention, according to self-reported intake and biomarker analyses. The primary end point was the rate of major cardiovascular events (myocardial infarction, stroke, or death from cardiovascular causes). We conducted a randomized trial of this diet pattern for the primary prevention of cardiovascular events. Patients admitted to the ICU after cardiac surgery, after liver transplantation, or for the treatment of burns were excluded. To address this uncertainty, we conducted the Saline versus Albumin Fluid Evaluation (SAFE) Study in 16 ICUs in Australia and New Zealand. All participants provided written informed consent. We tested the hypothesis that when 4 percent albumin is compared with 0.
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We conducted a multicenter, randomized, double-blind trial to compare the effect of fluid resuscitation with albumin or saline on mortality in a heterogeneous population of patients in the ICU. Full Text of Methods. None of the sponsors had any role in the trial design, data analysis, or reporting of the results. 10-12 The trial was designed and conducted by the authors, and the protocol was approved by the institutional review boards at all study locations. Eligible patients were those whom the treating clinician judged to require fluid administration to maintain or increase intravascular volume, with this decision supported by the fulfillment of at least one objective criterion. A primary end-point event occurred in 288 participants. Detailed enrollment criteria are provided in the Supplementary Appendix, available at NEJM. Abstract Background Observational cohort studies and a secondary prevention trial have shown an inverse association between adherence to the Mediterranean diet and cardiovascular risk. Methods In a multicenter trial in Spain, we randomly assigned participants who were at high cardiovascular risk, but with no cardiovascular disease at enrollment, to one of three diets: a Mediterranean diet supplemented with extra-virgin olive oil, a Mediterranean diet supplemented with mixed nuts, or a control diet (advice to reduce dietary fat). On the basis of the results of an interim analysis, the trial was stopped after a median follow-up of 4. Details of the trial design are provided elsewhere. 9 percent sodium chloride (normal saline) for intravascular-fluid resuscitation in patients in the ICU, there is no difference in the 28-day rate of death from any cause. The primary outcome measure was death from any cause during the 28-day period after randomization. org.
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